Dr Helen Chappell



  • 2017- present: University Lecturer in Food Colloids, University of Leeds
  • 2016 - present: Visiting Researcher, DAMTP, University of Cambridge
  • 2016 - present: Affiliated Scholar, McDonald Institute for Archaeological Research, University of Cambridge
  • 2013 - 2016: Career Development Fellow, MRC, Human Nutrition Research, Cambridge
  • 2009 - 2013: Scientific Advisor, English Heritage, UK
  • 2006 - 2009: PDRA, Department of Earth Sciences, University of Cambridge


Helen is a member of the Department of Applied Mathematics and Theoretical Physics in Computational Biology. Her current research interests are in first-principles modelling (DFT); composite nanoparticles & complex structures; protein-particle interactions; nanoparticles in the gut; drug delivery; particle-membrane interactions and, bone health and structure.

Selected Publications

  • Chappell HF; Thom W; Bowron DT; Faria N; Hasnip PJ; Powell JJ (2017) Structure of naturally hydrated ferrihydrite revealed through neutron diffraction and first-principles modeling. Physical Review Materials1 (3), 036002.


  • Pele LC; Haas CT; Hewitt RE; Robertson J; Skepper J; Brown A; Hernandez-Garrido JC; Midgley PA; Faria N; Chappell H (2017) Synthetic mimetics of the endogenous gastrointestinal nanomineral: Silent constructs that trap macromolecules for intracellular delivery. Nanomedicine: Nanotechnology, Biology, and Medicine13 (2), pp. 619-630.


  • Marron AO; Chappell H; Ratcliffe S; Goldstein RE (2016) A model for the effects of germanium on silica biomineralization in choanoflagellates. Journal of The Royal Society Interface13 (122), pp. 20160485-20160485.


  • Friederichs RJ; Chappell HF; Shepherd DV; Best SM (2015) Synthesis, characterization and modelling of zinc and silicate co-substituted hydroxyapatite. Journal of The Royal Society Interface12 (108), pp. 20150190-20150190.