
Career
- 2016-present: Postdoctoral researcher, DAMTP, University of Cambridge, UK
- 2013-2015: Postdoctoral researcher, Institute of Genetics and Molecular and Cellular Biology (IGBMC), Strasbourg, France
- 2008-2012: Doctoral student and teaching assistent, Institue of Fluid Dynamics, ETH Zurich, Zurich, CH
- 2007 (summar intership): Graduate researcher, Learner Research Institute, Cleveland Clinic Foundation, Cleveland, USA
- 2007-2006 Bachelor/Master student (biomedical engineering), Politecnico di Milano, Milano, Italy
Research
I am a member of the Biological Physics research group in the Department of Applied Mathematics and Theoretical Physics (DAMTP). I am interested in the role of fluid flows and forces in the regulation and development of biological systems.
keywords: Cilia, Biological Stokesian Flows, Mechanotransduction, heart/valve development, embyonic heart, blood flow, inner ear, Benigne Paroxismal Positional Vertigo (BPPV), boundary and meshless numerical methods.
Links to Publications
Publications
CCDC61/VFL3 is a paralog of SAS6 and promotes ciliary functions
– Structure (London, England : 1993)
(2020)
28,
674
(DOI: 10.1016/j.str.2020.04.010)
Blood Flow Limits Endothelial Cell Extrusion in the Zebrafish Dorsal Aorta
– Cell reports
(2020)
31,
107505
(DOI: 10.1016/j.celrep.2020.03.069)
Three-dimensional microscopy and image analysis methodology for mapping and quantification of nuclear positions in tissues with approximate cylindrical geometry
– Philosophical transactions of the Royal Society of London. Series B, Biological sciences
(2018)
373,
20170332
(DOI: 10.1098/rstb.2017.0332)
Following Endocardial Tissue Movements via Cell Photoconversion in the Zebrafish Embryo.
– J Vis Exp
(2018)
2018,
ARTN e57290
(DOI: 10.3791/57290)
Anisotropic shear stress patterns predict the orientation of convergent tissue movements in the embryonic heart.
– Development (Cambridge, England)
(2017)
144,
4322
(DOI: 10.1242/dev.152124)
Hemodynamics driven cardiac valve morphogenesis
– Biochimica et biophysica acta
(2016)
1863,
1760
(DOI: 10.1016/j.bbamcr.2015.11.014)
Live imaging and modeling for shear stress quantification in the embryonic zebrafish heart
– Methods (San Diego, Calif.)
(2016)
94,
129
(DOI: 10.1016/j.ymeth.2015.09.017)
Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies.
– Cell Rep
(2015)
11,
1564
(DOI: 10.1016/j.celrep.2015.05.010)
Oscillatory flow modulates mechanosensitive klf2a expression through trpv4 and trpp2 during heart valve development
– Current biology : CB
(2015)
25,
1354
(DOI: 10.1016/j.cub.2015.03.038)
Blood flow mechanics in cardiovascular development.
– Cell Mol Life Sci
(2015)
72,
2545
(DOI: 10.1007/s00018-015-1885-3)
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