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Mason Medical Research Fellow

Career

  • 2019-present  Mason Medical Research Fellow, Department of Applied Mathematics and Theoretical Physics, University of Cambridge
  • 2019-present  Honorary Specialty Registrar in Infectious Diseases and Medical Microbiology, Cambridge University Hospitals
  • 2018-2019  Specialty Registrar in Infectious Diseases and Medical Microbiology, Cambridge University Hospitals
  • 2015-2018  Academic Clinical Fellow in Infectious Diseases, East of England Deanery
  • 2013-2015  Academic Foundation Programme doctor, Brighton and Sussex University Hospitals
  • 2009-2013  Student, Cambridge Graduate Course in Medicine
  • 2006-2009  Ph.D. in theoretical physics, Department of Applied Mathematics and Theoretical Physics, University of Cambridge

Research Interests

I am a clinical academic working in the Disease Dynamics group. My research interests lie at the interface between mathematics and molecular virology. I work to develop and apply novel signal processing algorithms to viral genetic data with a view to discovery of previously unrecognised regions of structural and/or functional importance in viruses. This allows us to understand better the life cycle and pathogenicity of these agents and so focus on how we can disrupt the life cycle and avoid, attenuate or cure disease. At present my focus is on flaviviruses (including, amongst others, dengue, Zika, yellow fever and tick-borne encephalitis viruses); I also have some ongoing work into HIV.

Publications

The following is a selection of publications. For a full list, please see my ORCID profile.

  • A scale-free analysis of the HIV-1 genome demonstrates multiple conserved regions of structural and functional importance. Jordan P. Skittrall, Carin K. Ingemarsdotter, Julia R. Gog, Andrew M.L. Lever. PLoS Comput Biol 15(9): e1007345.
  • A new method for detecting signal regions in ordered sequences of real numbers, and application to viral genomic data. Julia R. Gog, Andrew M.L. Lever, Jordan P. Skittrall. PLoS ONE 13(4): e0195763.

A Selection of Links

Publications

Specificity and positive predictive value of SARS-CoV-2 nucleic acid amplification testing in a low-prevalence setting
JP Skittrall, M Wilson, AA Smielewska, S Parmar, MD Fortune, D Sparkes, MD Curran, H Zhang, H Jalal
– Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
(2020)
Point of Care Nucleic Acid Testing for SARS-CoV-2 in Hospitalized Patients: A Clinical Validation Trial and Implementation Study
DA Collier, SM Assennato, B Warne, N Sithole, K Sharrocks, A Ritchie, P Ravji, M Routledge, D Sparkes, J Skittrall, A Smielewska, I Ramsey, N Goel, M Curran, D Enoch, R Tassell, M Lineham, D Vaghela, C Leong, HP Mok, J Bradley, KGC Smith, V Mendoza, N Demiris, M Besser, G Dougan, PJ Lehner, MJ Siedner, H Zhang, CS Waddington, H Lee, RK Gupta, CITIID-NIHR COVID BioResource Collaboration
– Cell Rep Med
(2020)
1,
100062
Cross-sectional study of the prevalence, causes and management of hospital-onset diarrhoea.
D Mawer, F Byrne, S Drake, C Brown, A Prescott, B Warne, R Bousfield, JP Skittrall, I Ramsay, D Somasunderam, M Bevan, J Coslett, J Rao, P Stanley, A Kennedy, R Dobson, S Long, T Obisanya, T Esmailji, C Petridou, K Saeed, K Brechany, K Davis-Blue, H O'Horan, B Wake, J Martin, J Featherstone, C Hall, J Allen, G Johnson, C Hornigold, N Amir, K Henderson, C McClements, I Liew, A Deshpande, E Vink, D Trigg, J Guilfoyle, M Scarborough, C Scarborough, THN Wong, T Walker, N Fawcett, G Morris, K Tomlin, C Grix, E O'Cofaigh, D McCaffrey, M Cooper, K Corbett, K French, S Harper, C Hayward, M Reid, V Whatley, J Winfield, S Hoque, L Kelly, I King, A Bradley, B McCullagh, C Hibberd, M Merron, C McCabe, S Horridge, J Taylor, S Koo, F Elsanousi, R Saunders, F Lim, A Bond, S Stone, ID Milligan, DJF Mack, A Nagar, RM West, MH Wilcox, A Kirby, JAT Sandoe
– Journal of Hospital Infection
(2019)
103,
200
A scale-free analysis of the HIV-1 genome demonstrates multiple conserved regions of structural and functional importance.
J Skittrall, C Ingemarsdotter, J Gog, A Lever
– PLoS Comput. Biol.
(2019)
15,
e1007345
Use of a Retrospective Methodology to Examine the Process of Care Surrounding Serious Medical Events in HIV-Positive Patients: A Feasibility Study.
ERM Pool, V Cooper, E Youssef, J Wright, J Skittrall, O Blach, M Fisher, H Smith
– Journal of the International Association of Providers of AIDS Care (JIAPAC)
(2019)
18,
2325958219868747
A new method for detecting signal regions in ordered sequences of real numbers, and application to viral genomic data
JR Gog, AML Lever, JP Skittrall
– PLoS One
(2018)
13,
e0195763
The changing face of bacteraemia in an HIV-1 positive cohort in the United Kingdom
AN Bryce, JP Skittrall, Y Gilleece, C Sargent
– J Infect
(2017)
74,
325
An ageing population and changing UK bacteraemia profile may affect the characteristics and microbiology of infective spondylodiscitis.
J Donovan, JP Skittrall, T Moore, C Sargent, D Agranoff, M Llewelyn
– Journal of Infection
(2016)
73,
91
Rigid sigmoidoscopy: No contamination of the sigmoidoscopist's face with faecal flora in a small study
JP Skittrall, L Eid-Arimoku, M Joshi, MJ Newport, EM Moore
– The Journal of hospital infection
(2016)
93,
112
Drug Reaction, Eosinophilia and Systemic Symptoms (DRESS) syndrome secondary to allopurinol with early lymphadenopathy and symptom relapse.
R Turney, JP Skittrall, J Donovan, D Agranoff
– BMJ Case Reports
(2015)
2015,
bcr2015211222
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Research Group

Disease Dynamics

Room

G0.04

Telephone

01223 339896