![]() |
Simon Tavaré FRS, FMedSciDept of Applied Mathematics and Theoretical PhysicsUniversity of Cambridge Centre for Mathematical Sciences Wilberforce Road Cambridge CB3 0WA Phone: + 44 1223 760420 FAX: +44 1223 765900 Email: st321 at cam dot ac dot uk |
![]() |
I am a Professorial Fellow of Christ's College, and have been a Professor in the
Department of Applied Mathematics and Theoretical Physics at the University of Cambridge since 2003. I am chairman of the management committee of the
Cambridge Computational Biology Institute, Co-Director of its MPhil in Computational and Systems Biology and Director of its new Wellcome Trust 4-year PhD program in Mathematical Genomics and Medicine. I am a Fellow of the Society of Biology (FSB) and the Institute of Mathematics and its Applications (FIMA), and in 2011 I was elected as a Fellow of the Royal Society (FRS).
My research in DAMTP focusses on stochastic computation methods such as MCMC without likelihoods and approximate Bayesian computation; on theoretical population genetics, including inference for coalescent processes; and statistical genetics, including novel methods for identifying interacting features in association studies.
I am also Professor of Cancer Research (Bioinformatics) in the Department of Oncology and Senior Group Leader in the Cancer Research UK Cambridge Research Institute (CRI). In 2009 I was elected as a Fellow of the Academy of Medical Sciences (FMedSci), and I am serving on Council during 2011-2014.
Our research in the CRI focusses on cancer genomics, primarily the statistical analysis of microarray and second-generation sequencing technologies to study e.g. gDNA, expression, methylation, microRNAs and transcription factor binding. We have a particular emphasis on analysis of data from Illumina platforms. With Rebecca Fitzgerald we have recently begun a CRUK-funded International Cancer Genome Consortium project to sequence 500 matched oesophageal adenocarcinoma-normal pairs. A second theme is the development of statistical and stochastic methods (such as cellular Potts models) arising in evolutionary approaches to cancer. We have developed a high-throughput experimental method for identifying methylation status in single molecules that we use to study tissue evolution. Further details of our research at the CRI may be found here.
I am an associate editor of Annals of Human Genetics, Journal of Computational Biology and Statistics Surveys, on the Editorial Board of CaPR (Cancer Prevention Research), MathematicS In Action, Human Genomics, and Evolutionary Bioinformatics Online. and past Associate Editor or Editorial Board member for 12 other journals in probability, statistics and biology.
I have a long-standing connection with the Program in Molecular and Computational Biology at the University of Southern California, where I am a Research Professor and hold the George and Louise Kawamoto Chair in Biological Sciences. Further information may be found here.
We are supported by grants from BBSRC, EPSRC, MRC and Cancer Research UK.
Associate Scientist
Research Associates
Senior Scientific Officer
Research Students
Research Visitors
Former Postdocs
Former Research Students
Former Systems Assistants
http://www.damtp.cam.ac.uk/user/st321/index.html, 8 February 2012 |