Career
- 2018-date: Royal Society E.P. Abraham Professor, DAMPT, Cambridge
- 2011-date: Herchel Smith Chair in Physics, Cavendish Laboratory,
- Cambridge
- 2002-2010: Personal Chair in the Theory of Condensed Matter, Cavendish Laboratory,
- Cambridge
- 2000-2002: University Readership in the Theory of Condensed Matter, Cavendish Laboratory, Cambridge
- 1995-1999: Lecturer, Cavendish Laboratory, Cambridge
- 1995-date: Fellow, St John’s College, Cambridge
- 1994-1995: Royal Society Research Fellow and Lecturer, Imperial College, London
- 1990-1991: Junior Research Fellow, Gonville and Caius College, Cambridge
Research
Ben is a member the Department of Applied Mathematics and Theoretical Physics and the Cavendish Laboratory, Department of Physics. He also holds affiliated positions in the Wellcome Trust/CRUK Gurdon Institute and the Wellcome Trust/MRC Stem Cell Institute. His research interests have spanned a wide range of topics within the area of theoretical quantum condensed matter physics. However, his current interests are focussed on the application of modelling approaches to study the dynamics of biological systems, from subcellular processes, to cell fate decision-making and morphogenic processes. His research is supported by grants from EPSRC, the Wellcome Trust, CRUK and the Royal Society.
Selected Publications
- S. Rulands, et al., Universality of clone dynamics during tissue development, Nature Physics 14, 469-474 (2018)
- E. Hannezo, et al., A unifying theory of branching morphogenesis, Cell 171, 242-255 (2017)
- X. Lan, et al., Cell fate mapping of human glioblastoma reveals an invariant stem cell hierarchy pre- and post-treatment, Nature 549, 227-232 (2017)
- A. Sanchez-Danes, et al., Defining the clonal dynamics leading to tumor initiation, Nature 536, 298-303 (2016)
- B. D. Simons and H. Clevers, Strategies of stem cell self-renewal in adult tissues, Cell 145, 851-862 (2011)
- C. Lopez-Garcia, et al., Intestinal stem cell replacement follows a pattern of neutral drift, Science 330, 822-825 (2010)
Publications
Distinct contribution of stem and progenitor cells to epidermal maintenance
– Nature
(2012)
489,
257
(doi: 10.1038/nature11393)
How variable clones build an invariant retina.
– Neuron
(2012)
75,
786
(doi: 10.1016/j.neuron.2012.06.033)
Defining the mode of tumour growth by clonal analysis
– Nature
(2012)
488,
527
(doi: 10.1038/nature11344)
A single progenitor population switches behavior to maintain and repair esophageal epithelium
– Science
(2012)
337,
1091
(doi: 10.1126/science.1218835)
Drosophila midgut homeostasis involves neutral competition between symmetrically dividing intestinal stem cells.
– The EMBO Journal
(2012)
31,
2473
(doi: 10.1038/emboj.2012.106)
Discrete symmetry breaking transitions between paired superfluids
– Physical Review A
(2012)
85,
033636
(doi: 10.1103/physreva.85.033636)
Stem cell self-renewal in intestinal crypt
– Experimental Cell Research
(2011)
317,
2719
(doi: 10.1016/j.yexcr.2011.07.010)
Dynamics of nonequilibrium Dicke models
– Physical Review A Atomic Molecular and Optical Physics
(2011)
85,
013817
(doi: 10.1103/PhysRevA.85.013817)
Magnetic properties of the second Mott lobe in pairing Hamiltonians
– Physical Review A
(2011)
84,
023635
(doi: 10.1103/physreva.84.023635)
Universal patterns of stem cell fate in cycling adult tissues.
– Development (Cambridge, England)
(2011)
138,
3103
(doi: 10.1242/dev.060103)
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