Career
- 2018-date: Royal Society E.P. Abraham Professor, DAMPT, Cambridge
- 2011-date: Herchel Smith Chair in Physics, Cavendish Laboratory,
- Cambridge
- 2002-2010: Personal Chair in the Theory of Condensed Matter, Cavendish Laboratory,
- Cambridge
- 2000-2002: University Readership in the Theory of Condensed Matter, Cavendish Laboratory, Cambridge
- 1995-1999: Lecturer, Cavendish Laboratory, Cambridge
- 1995-date: Fellow, St John’s College, Cambridge
- 1994-1995: Royal Society Research Fellow and Lecturer, Imperial College, London
- 1990-1991: Junior Research Fellow, Gonville and Caius College, Cambridge
Research
Ben is a member the Department of Applied Mathematics and Theoretical Physics and the Cavendish Laboratory, Department of Physics. He also holds affiliated positions in the Wellcome Trust/CRUK Gurdon Institute and the Wellcome Trust/MRC Stem Cell Institute. His research interests have spanned a wide range of topics within the area of theoretical quantum condensed matter physics. However, his current interests are focussed on the application of modelling approaches to study the dynamics of biological systems, from subcellular processes, to cell fate decision-making and morphogenic processes. His research is supported by grants from EPSRC, the Wellcome Trust, CRUK and the Royal Society.
Selected Publications
- S. Rulands, et al., Universality of clone dynamics during tissue development, Nature Physics 14, 469-474 (2018)
- E. Hannezo, et al., A unifying theory of branching morphogenesis, Cell 171, 242-255 (2017)
- X. Lan, et al., Cell fate mapping of human glioblastoma reveals an invariant stem cell hierarchy pre- and post-treatment, Nature 549, 227-232 (2017)
- A. Sanchez-Danes, et al., Defining the clonal dynamics leading to tumor initiation, Nature 536, 298-303 (2016)
- B. D. Simons and H. Clevers, Strategies of stem cell self-renewal in adult tissues, Cell 145, 851-862 (2011)
- C. Lopez-Garcia, et al., Intestinal stem cell replacement follows a pattern of neutral drift, Science 330, 822-825 (2010)
Publications
Strategies for homeostatic stem cell self-renewal in adult tissues.
– Cell
(2011)
145,
851
(doi: 10.1016/j.cell.2011.05.033)
Patterning as a signature of human epidermal stem cell regulation
– J R Soc Interface
(2011)
8,
1815
(doi: 10.1098/rsif.2011.0240)
Ising Deconfinement Transition between Feshbach-Resonant Superfluids
– Phys Rev Lett
(2011)
106,
015303
Reconstruction of rat retinal progenitor cell lineages in vitro reveals a surprising degree of stochasticity in cell fate decisions.
– Development
(2010)
138,
227
(doi: 10.1242/dev.059683)
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells.
– Cell
(2010)
143,
134
(doi: 10.1016/j.cell.2010.09.016)
Intestinal stem cell replacement follows a pattern of neutral drift
– Science
(2010)
330,
822
(doi: 10.1126/science.1196236)
Mouse Germ Line Stem Cells Undergo Rapid and Stochastic Turnover
– Cell Stem Cell
(2010)
7,
214
(doi: 10.1016/j.stem.2010.05.017)
Quantum phase transitions in bosonic heteronuclear pairing Hamiltonians
– Physical Review A
(2010)
82,
013639
(doi: 10.1103/PhysRevA.82.013639)
Collective dynamics of Bose-Einstein condensates in optical cavities
– Phys Rev Lett
(2010)
105,
043001
Exciton front propagation in photoexcited GaAs quantum wells
– Physical Review B
(2010)
81,
115320
(doi: 10.1103/physrevb.81.115320)
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