Career
- 2013-date: Senior Research Associate, University of Cambridge, Cambridge UK
- 2008-2012: Postdoctoral Research Associate, University of Cambridge, Cambridge UK
- 2000-2007: PhD. in Genetics, Harvard Medical School, Boston, USA
- 1995-1999: B.A. in Biological Sciences, Cornell University, Ithaca, USA
Research
Kyriacos is a member of the Department of Applied Mathematics and Theoretical Physics, Biological Physics group. His current research interests are flagellar dynamics and the mechanisms of how micro-organisms steer towards to or away from stimuli.
Selected Publications
- Leptos, K.C., Wan, K.Y., Polin, M., Tuval, I., Pesci, A.I., Goldstein, R.E. Antiphase synchronization in a flagellar-dominance mutant of Chlamydomonas, Phys Rev Lett 2013. Oct; 111 (15): p. 158101
- Helliwell, K.E., Wheeler, G.L., Leptos, K.C., Goldstein, R.E., Smith, A.G. Insights into the evolution of vitamin B12 auxotrophy from sequenced algal genomes, Mol Bio Evol 2011. Oct; 28 (10): p.2921
- Leptos, K.C., Guasto, J.S., Gollub, J.P., Pesci, A.I., Goldstein, R.E. Dynamics of enhanced tracer diffusion in suspensions of swimming eukaryotic microorganisms, Phys Rev Lett 2009. Nov; 103 (19): p. 198103
- Drescher, K., Leptos, K.C., Tuval, I., Ishikawa, T., Pedley, T.J., and Goldstein, R.E. Dancing Volvox: Hydrodynamic bound states of swimming algae, Phys Rev Lett 2009. Apr; 102 (16): p. 168101-4.
- Drescher, K., Leptos, K.C., Goldstein, R.E. How to track protists in three dimensions, Rev Sci Instrum 2009. Jan; 80 (1): p. 014301.
- Jaffe, J.D., Mani, D.R., Leptos, K.C., Church, G.M., Mootha, V.K. and Carr, S.A.: PEPPeR: A platform for experimental proteomic pattern recognition, Mol Cell Proteomics 2006. Oct; 5 (10): p. 1927-41.
- Leptos, K.C., Sarracino, D.A., Jaffe, J.D., Krastins, B. and Church, G.M. MapQuant: New open-source software for large-scale protein quantification, Proteomics 2006. Mar; 6 (6): p. 1770-82
Publications
Phototaxis of Chlamydomonas arises from a tuned adaptive photoresponse shared with multicellular Volvocine green algae.
– Physical Review E: Statistical, Nonlinear, and Soft Matter Physics
(2023)
107,
014404
(doi: 10.1103/PhysRevE.107.014404)
Adaptive phototaxis of Chlamydomonas and the evolutionary transition to multicellularity in Volvocine green algae
(2022)
(doi: 10.1101/2022.07.24.500296)
The fluid dynamics of collective vortex structures of plant-animal worms
– Journal of Fluid Mechanics
(2021)
914,
a20
(doi: 10.1017/jfm.2020.1112)
The fluid dynamics of collective vortex structures of plant-animal worms
(2020)
2020.11.04.366658
(doi: 10.1101/2020.11.04.366658)
Diurnal Variations in the Motility of Populations of Biflagellate Microalgae.
– Biophysical Journal
(2020)
119,
2055
(doi: 10.1016/j.bpj.2020.10.006)
An Adaptive Flagellar Photoresponse Determines the Dynamics of Accurate Phototactic Steering in Chlamydomonas
(2018)
(doi: 10.1101/254714)
Lag, lock, sync, slip: the many 'phases' of coupled flagella
– J R Soc Interface
(2014)
11,
20131160
(doi: 10.1098/rsif.2013.1160)
Antiphase synchronization in a flagellar-dominance mutant of Chlamydomonas.
– Physical Review Letters
(2013)
111,
158101
Insights into the evolution of vitamin B12 auxotrophy from sequenced algal genomes.
– Molecular biology and evolution
(2011)
28,
2921
(doi: 10.1093/molbev/msr124)
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