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Department of Applied Mathematics and Theoretical Physics

Education

  • 2001-2007: PhD, MIT/WHOI Joint Program in Biological Oceanography

Research

Petra is a member of the Department of Applied Mathematics and Theoretical Physics, belonging to Infectious Disease Dynamics research group. Her work draws on optimal control and game theory to find how heterogeneities in demographic and socio-economic factors influence and shape optimal strategies for control of infectious diseases. 

Selected Publications

  • Klepac, P., Metcalf, C. J. E., McLean, A. and Hampson, K. (2013) Towards the endgame and beyond: complexities and challenges for the elimination of infectious diseases. Philosophical Transactions of the Royal Society B 368: 20120137. [open access]
  • Henderson, D. A. and Klepac, P. (2013) Lessons from the eradication of smallpox: an interview with DA Henderson. Philosophical Transactions of the Royal Society B368: 20130113. [open access]
  • Klepac, P., Metcalf, C.J.E., Bjørnstad, O. N. and Grenfell, B.T. (2012) Optimizing reactive responses to outbreaks of immunizing infections: balancing case management and vaccination. PLOS ONE 8:e41428. [open access]
  • Klepac, P., Laxminarayan, R. and Grenfell, B. T. (2011) Synthesizing epidemiological and economic optima for control of immunizing infections. Proceedings of the National Academy of Sciences 108: 14366–14370. [open access]
  • Klepac, P. and Caswell, H. (2011) The stage-structured epidemic: linking disease and demography with a multi-state matrix model approach. Theoretical Ecology 4: 301-319.

Publications

Lessons from the eradication of smallpox: an interview with D. A. Henderson
DA Henderson, P Klepac
– Philosophical transactions of the Royal Society of London. Series B, Biological sciences
(2013)
368,
20130113
Towards the endgame and beyond: Complexities and challenges for the elimination of infectious diseases
P Klepac, CJE Metcalf, AR McLean, K Hampson
(2013)
368,
20120137
Lessons from the eradication of smallpox: an interview with D. A. Henderson
DA Henderson, P Klepac
– Philosophical Transactions of the Royal Society: Biological Sciences
(2013)
368,
20130113
Towards the endgame and beyond: complexities and challenges for the elimination of infectious diseases
P Klepac, CJE Metcalf, AR McLean, K Hampson
– Philosophical Transactions of the Royal Society
(2013)
368,
20120137
Implications of spatially heterogeneous vaccination coverage for the risk of congenital rubella syndrome in South Africa
CJE Metcalf, C Cohen, J Lessler, JM McAnerney, GM Ntshoe, A Puren, P Klepac, A Tatem, BT Grenfell, ON Bjørnstad
– Journal of The Royal Society Interface
(2013)
10,
20120756
Structured models of infectious disease: Inference with discrete data
CJE Metcalf, J Lessler, P Klepac, A Morice, BT Grenfell, ON Bjørnstad
– Theoretical Population Biology
(2012)
82,
275
Optimizing reactive responses to outbreaks of immunizing infections: balancing case management and vaccination.
P Klepac, ON Bjørnstad, CJE Metcalf, BT Grenfell
– PLoS One
(2012)
7,
e41428
Impact of birth rate, seasonality and transmission rate on minimum levels of coverage needed for rubella vaccination
CJE Metcalf, J Lessler, P Klepac, F Cutts, BT Grenfell
– Epidemiol Infect
(2012)
140,
2290
Structured models of infectious disease: Inference with discrete data
CJE Metcalf, J Lessler, P Klepac, A Morice, BT Grenfell, ON Bjørnstad
– Theoretical Population Biology
(2011)
82,
275
Synthesizing epidemiological and economic optima for control of immunizing infections
P Klepac, R Laxminarayan, BT Grenfell
– Proceedings of the National Academy of Sciences
(2011)
108,
14366
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Research Group

Disease Dynamics

Room

G0.04

Telephone

01223 339896

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