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Department of Applied Mathematics and Theoretical Physics

Professor Stephen John Eglen

Career

  • 1997-2000 Wellcome Trust Fellow in Mathematical Biology, Edinburgh
  • 2000-2001 Lecturer, School of Informatics, Edinburgh
  • 2001-2004 Wellcome Trust Travelling Fellowship, St Louis and Edinburgh
  • 2004-2006 Lecturer, DAMTP
  • 2006-2015 Senior Lecturer, DAMTP
  • 2015- Reader. DAMTP

Research

Stephen Eglen is a computational neuroscientist: he uses computational methods to study the development of the nervous system, using mostly the retina and other parts of the visual pathway as a model system. He is particularly interested in questions of structural and functional development:

Structural development: how do retinal neurons acquire their positional information within a circuit?

Functional development: what are the mechanisms by which neurons make contact with each other, to perform functioning circuits?

Selected Publications

Please see my publications page

Publications

Following the ontogeny of retinal waves: pan-retinal recordings of population dynamics in the neonatal mouse.
A Maccione, MH Hennig, M Gandolfo, O Muthmann, J van Coppenhagen, SJ Eglen, L Berdondini, E Sernagor
– J Physiol
(2013)
592,
1545
(doi: 10.1113/jphysiol.2013.262840)
A data repository and analysis framework for spontaneous neural activity recordings in developing retina
S Eglen, M Weeks, M Jessop, J Simonotto, T Jackson, E Sernagor
(2013)
(doi: 10.1101/000455)
Neural circuits for peristaltic wave propagation in crawling Drosophila larvae: analysis and modeling.
J Gjorgjieva, J Berni, JF Evers, SJ Eglen
– Frontiers in computational neuroscience
(2013)
7,
24
(doi: 10.3389/fncom.2013.00024)
Following the assembly of functional circuitry: high resolution large-scale population neuronal dynamics in the neonatal mouse retina
A Maccione, MH Hennig, M Gandolfo, O Muthmann, M Down, CJ van, A Jones, SJ Eglen, L Berdondini, E Sernagor
(2013)
Parasol cell mosaics are unlikely to drive the formation of structured orientation maps in primary visual cortex
VRA Hore, JB Troy, SJ Eglen
– Visual neuroscience
(2012)
29,
283
(doi: 10.1017/s0952523812000338)
GABAergic CONTROL OF RETINAL GANGLION CELL DENDRITIC DEVELOPMENT
FP Chabrol, SJ Eglen, E Sernagor
– Neuroscience
(2012)
227,
30
(doi: 10.1016/j.neuroscience.2012.09.040)
Neuronal clustering and fasciculation phenotype in Dscam- and Bax-deficient mouse retinas
PW Keeley, B Sliff, SC Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese
– The Journal of comparative neurology
(2012)
520,
2041
(doi: 10.1002/cne.23027)
Neuronal clustering and fasciculation phenotype in Dscam‐ and Bax‐deficient mouse retinas
PW Keeley, BJ Sliff, SC Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese
– Journal of Comparative Neurology
(2012)
520,
spc1
(doi: 10.1002/cne.23089)
Neuronal clustering and fasciculation phenotype in Dscam- and Bax-deficient mouse retinas
PW Keeley, BJ Sliff, SCS Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese
– J Comp Neurol
(2012)
520,
1349
(doi: 10.1002/cne.23033)
Cellular Spacing: Analysis and Modelling of Retinal Mosaics
SJ Eglen
(2012)
365
(doi: 10.1007/978-94-007-3858-4_12)
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Research Group

Computational Biology

Email

S.J.Eglen@damtp.cam.ac.uk

Room

G0.11

Personal homepage

http://www.damtp.cam.ac.uk/user/sje30/

Study at Cambridge

About the University

Research at Cambridge