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Department of Applied Mathematics and Theoretical Physics

Professor Stephen John Eglen

Career

  • 1997-2000 Wellcome Trust Fellow in Mathematical Biology, Edinburgh
  • 2000-2001 Lecturer, School of Informatics, Edinburgh
  • 2001-2004 Wellcome Trust Travelling Fellowship, St Louis and Edinburgh
  • 2004-2006 Lecturer, DAMTP
  • 2006-2015 Senior Lecturer, DAMTP
  • 2015- Reader. DAMTP

Research

Stephen Eglen is a computational neuroscientist: he uses computational methods to study the development of the nervous system, using mostly the retina and other parts of the visual pathway as a model system. He is particularly interested in questions of structural and functional development:

Structural development: how do retinal neurons acquire their positional information within a circuit?

Functional development: what are the mechanisms by which neurons make contact with each other, to perform functioning circuits?

Selected Publications

Please see my publications page

Publications

Mecp2 deficiency impairs microscale cortical network topology and dynamics in a Rett syndrome mouse model.
AWE Dunn, TPH Sit, RC Feord, A Soltani, Y Yuan, R Turner, I Loureiro, SJ Eglen, O Paulsen, SB Mierau
– bioRxiv
(2025)
(doi: 10.64898/2025.12.17.694950)
Beyond the numbers: advancing responsible research assessment report
L Meehan, E Byrne, N Tal-Perry, L Woolhouse, S Eglen, N Swann
(2025)
(doi: 10.17863/CAM.125218)
Homophilic wiring principles underpin neuronal network topology in vitro.
D Akarca, AWE Dunn, PJ Hornauer, S Ronchi, M Fiscella, C Wang, M Terrigno, R Jagasia, PE Vértes, SB Mierau, O Paulsen, SJ Eglen, A Hierlemann, DE Astle, M Schröter
– eLife
(2025)
14,
e85300
(doi: 10.7554/eLife.85300)
MEA-NAP: A flexible network analysis pipeline for neuronal 2D and 3D organoid multielectrode recordings.
TPH Sit, RC Feord, AWE Dunn, J Chabros, D Oluigbo, HH Smith, L Burn, E Chang, A Boschi, Y Yuan, GM Gibbons, M Khayat-Khoei, F De Angelis, E Hemberg, M Hemberg, MA Lancaster, A Lakatos, SJ Eglen, O Paulsen, SB Mierau
– Cell Reports Methods
(2024)
4,
100901
(doi: 10.1016/j.crmeth.2024.100901)
Effects of long-term transcutaneous auricular vagus nerve stimulation on circadian vagal activity in people with Prader-Willi Syndrome: A case-series.
M Schmausser, A Holland, J Beresford-Webb, SJ Eglen, K Manning, L Aman, D Kronhaus, J Koenig
– Research in Developmental Disabilities
(2024)
154,
104855
(doi: 10.1016/j.ridd.2024.104855)
Application of the Sepsis-3 criteria to describe sepsis epidemiology in the Amsterdam UMCdb intensive care dataset.
CYK Williams, T Edinburgh, PWG Elbers, PJ Thoral, A Ercole
– PLoS One
(2024)
19,
e0304133
(doi: 10.1371/journal.pone.0304133)
MEA-NAP compares microscale functional connectivity, topology, and network dynamics in organoid or monolayer neuronal cultures
TP Sit, RC Feord, AW Dunn, J Chabros, D Oluigbo, HH Smith, L Burn, E Chang, A Boschi, Y Yuan, GM Gibbons, M Khayat-Khoei, F De Angelis, E Hemberg, M Hemberg, MA Lancaster, A Lakatos, SJ Eglen, O Paulsen, SB Mierau
(2024)
(doi: 10.1101/2024.02.05.578738)
Rights Retention Strategy: a Primer from UKRN
R Network, S Eglen
(2023)
(doi: 10.31219/osf.io/2ajsg)
Bayesian model selection for multilevel models using integrated likelihoods
T Edinburgh, A Ercole, S Eglen
– Plos One
(2023)
18,
e0280046
(doi: 10.48550/arxiv.2207.02144)
Bayesian model selection for multilevel models using integrated likelihoods
T Edinburgh, A Ercole, SJ Eglen
(2022)
(doi: 10.48550/arxiv.2207.02144)
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Research Group

Computational Biology

Email

S.J.Eglen@damtp.cam.ac.uk

Room

G0.11

Personal homepage

http://www.damtp.cam.ac.uk/user/sje30/

Study at Cambridge

About the University

Research at Cambridge