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Department of Applied Mathematics and Theoretical Physics

Dr Gamze Gursoy

Gamze is an Assistant Professor in the Department of Applied Mathematics and Theoretical Physics at the University of Cambridge. She previously served as the Herbert Irving Assistant Professor in the Department of Biomedical Informatics at Columbia University. Prior to joining Columbia, she completed a K99/R00 postdoctoral fellowship in computational biology at Yale University and earned her Ph.D. in Bioinformatics from the University of Illinois at Chicago. Further information on her group and her research can be found at g2lab.org

Publications

Integrating CSF and EV Proteomes Enhances Biomarker Discovery by Capturing Shared Variation Across Compartments
BRP Brown, X Li, MR Grasty, AD Miranker, G Gursoy
(2026)
(doi: 10.64898/2026.09.30.754912)
African green monkeys respond to synthetic Aβ oligomers with persistent Alzheimer’s-like activation
BRP Brown, X Li, MR Grasty, IR Lopez, S Dzigurski, MN Geradi, MR Weed, JD Elsworth, MS Lawrence, G Gürsoy, AD Miranker
– Communications Biology
(2026)
(doi: 10.1038/s42003-026-10968-5)
Privacy-preserving pangenome graphs
J Blindenbach, S Soni, G Gürsoy
– Nature Communications
(2026)
(doi: 10.1038/s41467-026-77591-0)
Private information leakage from polygenic risk scores.
K Nikitin, G Gursoy
– Genome Res
(2026)
gr.282202.126
(doi: 10.1101/gr.282202.126)
African Green Monkey Cerebrospinal Fluid miRNome Captures Conserved miRNAs Relevant to Human Neurodegenerative Disease.
S Dzigurski, R Al-Abri, X Li, MR Grasty, AC Rodrigues, MR Weed, JD Elsworth, MS Lawrence, YJ Heng, CS Bogsan, P Naderi Yeganeh, WA Hide, FJ Slack, G Gursoy, AD Miranker, BRP Brown
(2026)
(doi: 10.64898/2026.08.07.743104)
AE-AEPD: Repurposing Adversarial Evasion for Cross-Omics Linkage Defense
M Zohrabi, G Gursoy, R Bowler, K Kechris, F Banaei-Kashani
– ACM Bcb 2026 17th ACM International Conference on Bioinformatics Computational Biology and Health Informatics
(2026)
1
(doi: 10.1145/3807503.3819457)
The New York Genome Center ALS Consortium resource integrates postmortem tissue transcriptomics and whole genome sequencing to empower biological discovery.
J Humphrey, A Oku, M Byrska-Bishop, AO Basile, US Evani, A Corvelo, A Tokolyi, K Bp, A Réal, Y Kim, ML Bond, WE Clarke, R Fu, H Geiger, S Chang, T Naito, B Jang, R Musunuri, WH Dredge, R Al-Abri, BN Hoover, D Manaa, J McClintock, FP Singh, MH Pedersen, A Runnels, N Propp, S Fennessey, H-H Won, MC Zody, G Narzisi, N Robine, T Lappalainen, D Fagegaltier, G Gürsoy, DA Knowles, T Raj, NYGC ALS Consortium, MB Harms, H Phatnani
– medRxiv
(2026)
2026.04.29.26350889
(doi: 10.64898/2026.04.29.26350889)
pC-SAC: A method for high-resolution 3D genome reconstruction from low-resolution Hi-C data
JC Angel, N El Amraoui, G Gürsoy
– Nucleic Acids Res
(2025)
53,
gkaf289
(doi: 10.1093/nar/gkaf289)
Secure and scalable gene expression quantification with pQuant
S Hong, CR Walker, YA Choi, G Gürsoy
– Nat Commun
(2025)
16,
2380
(doi: 10.1038/s41467-025-57393-6)
Secure and federated quantitative trait loci mapping with privateQTL
YA Choi, Y Kim, P Miao, T Lappalainen, G Gürsoy
– Cell Genom
(2025)
5,
100769
(doi: 10.1016/j.xgen.2025.100769)
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Research Group

Computational Biology

Room

G1.11

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