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Department of Applied Mathematics and Theoretical Physics

Career

  • 1997-2000 Wellcome Trust Fellow in Mathematical Biology, Edinburgh
  • 2000-2001 Lecturer, School of Informatics, Edinburgh
  • 2001-2004 Wellcome Trust Travelling Fellowship, St Louis and Edinburgh
  • 2004-2006 Lecturer, DAMTP
  • 2006-2015 Senior Lecturer, DAMTP
  • 2015- Reader. DAMTP

Research

Stephen Eglen is a computational neuroscientist: he uses computational methods to study the development of the nervous system, using mostly the retina and other parts of the visual pathway as a model system. He is particularly interested in questions of structural and functional development:

Structural development: how do retinal neurons acquire their positional information within a circuit?

Functional development: what are the mechanisms by which neurons make contact with each other, to perform functioning circuits?

Selected Publications

Please see my publications page

Publications

Following the ontogeny of retinal waves: pan-retinal recordings of population dynamics in the neonatal mouse
A Maccione, MH Hennig, M Gandolfo, O Muthmann, J van Coppenhagen, SJ Eglen, L Berdondini, E Sernagor
– J Physiol
(2014)
592,
1545
Can retinal ganglion cell dipoles seed iso-orientation domains in the visual cortex?
M Schottdorf, SJ Eglen, F Wolf, W Keil
– PLoS ONE
(2014)
9,
e86139
A data repository and analysis framework for spontaneous neural activity recordings in developing retina
S Eglen, M Weeks, M Jessop, J Simonotto, T Jackson, E Sernagor
(2013)
Following the assembly of functional circuitry: high resolution large-scale population neuronal dynamics in the neonatal mouse retina
A Maccione, MH Hennig, M Gandolfo, O Muthmann, M Down, CJ van, A Jones, SJ Eglen, L Berdondini, E Sernagor
(2013)
Neural circuits for peristaltic wave propagation in crawling Drosophila larvae: analysis and modeling.
J Gjorgjieva, J Berni, JF Evers, SJ Eglen
– Frontiers in Computational Neuroscience
(2013)
7,
24
GABAergic control of retinal ganglion cell dendritic development
FP Chabrol, SJ Eglen, E Sernagor
– Neuroscience
(2012)
227,
30
Parasol cell mosaics are unlikely to drive the formation of structured orientation maps in primary visual cortex
VRA Hore, JB Troy, SJ Eglen
– Vis Neurosci
(2012)
29,
283
Neuronal clustering and fasciculation phenotype in Dscam- and Bax-deficient mouse retinas
PW Keeley, B Sliff, SC Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese
– The Journal of Comparative Neurology
(2012)
520,
2041
Neuronal clustering and fasciculation phenotype in Dscam‐ and Bax‐deficient mouse retinas
PW Keeley, BJ Sliff, SC Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese
– J Comp Neurol
(2012)
520,
spc1
Neuronal clustering and fasciculation phenotype in Dscam- and Bax-deficient mouse retinas
PW Keeley, BJ Sliff, SCS Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese
– J Comp Neurol
(2012)
520,
1349
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Research Group

Computational Biology

Room

G0.11