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Department of Applied Mathematics and Theoretical Physics

Professor Stephen John Eglen

Career

  • 1997-2000 Wellcome Trust Fellow in Mathematical Biology, Edinburgh
  • 2000-2001 Lecturer, School of Informatics, Edinburgh
  • 2001-2004 Wellcome Trust Travelling Fellowship, St Louis and Edinburgh
  • 2004-2006 Lecturer, DAMTP
  • 2006-2015 Senior Lecturer, DAMTP
  • 2015- Reader. DAMTP

Research

Stephen Eglen is a computational neuroscientist: he uses computational methods to study the development of the nervous system, using mostly the retina and other parts of the visual pathway as a model system. He is particularly interested in questions of structural and functional development:

Structural development: how do retinal neurons acquire their positional information within a circuit?

Functional development: what are the mechanisms by which neurons make contact with each other, to perform functioning circuits?

Selected Publications

Please see my publications page

Publications

A data repository and analysis framework for spontaneous neural activity recordings in developing retina
SJ Eglen, M Weeks, M Jessop, J Simonotto, T Jackson, E Sernagor
– Gigascience
(2014)
3,
2047-217x-3-3
(doi: 10.1186/2047-217x-3-3)
Can Retinal Ganglion Cell Dipoles Seed Iso-Orientation Domains in the Visual Cortex?
M Schottdorf, SJ Eglen, F Wolf, W Keil
– Plos One
(2014)
9,
e86139
(doi: 10.1371/journal.pone.0086139)
Retinotopic Development, Models of
SJ Eglen
(2014)
1
(doi: 10.1007/978-1-4614-7320-6_406-1)
Following the ontogeny of retinal waves: pan-retinal recordings of population dynamics in the neonatal mouse.
A Maccione, MH Hennig, M Gandolfo, O Muthmann, J van Coppenhagen, SJ Eglen, L Berdondini, E Sernagor
– The Journal of physiology
(2013)
592,
1545
(doi: 10.1113/jphysiol.2013.262840)
A data repository and analysis framework for spontaneous neural activity recordings in developing retina
SJ Eglen, M Weeks, M Jessop, J Simonotto, T Jackson, E Sernagor
(2013)
(doi: 10.1101/000455)
Neural circuits for peristaltic wave propagation in crawling Drosophila larvae: analysis and modeling.
J Gjorgjieva, J Berni, JF Evers, SJ Eglen
– Frontiers in Computational Neuroscience
(2013)
7,
24
(doi: 10.3389/fncom.2013.00024)
Following the assembly of functional circuitry: high resolution large-scale population neuronal dynamics in the neonatal mouse retina
A Maccione, MH Hennig, M Gandolfo, O Muthmann, M Down, CJ van, A Jones, SJ Eglen, L Berdondini, E Sernagor
(2013)
Parasol cell mosaics are unlikely to drive the formation of structured orientation maps in primary visual cortex
VRA Hore, JB Troy, SJ Eglen
– Visual Neuroscience
(2012)
29,
283
(doi: 10.1017/S0952523812000338)
GABAergic control of retinal ganglion cell dendritic development.
FP Chabrol, SJ Eglen, E Sernagor
– Neuroscience
(2012)
227,
30
(doi: 10.1016/j.neuroscience.2012.09.040)
Compensatory redistribution of neuroligins and N‐cadherin following deletion of synaptic β1‐integrin
PW Keeley, B Sliff, SC Lee, PG Fuerst, RW Burgess, SJ Eglen, BE Reese
– Journal of Comparative Neurology
(2012)
520,
1349
(doi: 10.1002/cne.23033)
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Research Group

Computational Biology

Email

S.J.Eglen@damtp.cam.ac.uk

Room

G0.11

Personal homepage

http://www.damtp.cam.ac.uk/user/sje30/

Study at Cambridge

About the University

Research at Cambridge